In the field of musculoskeletal (MSK) disease management, the role of biomechanics cannot be overstated. Biomechanics, the study of the mechanical forces and movements that occur within the human body, plays a pivotal role in understanding and improving the functioning of the musculoskeletal system. This is particularly crucial in the context of musculoskeletal diseases, such as knee osteoarthritis (KOA), which often require targeted approaches to restore mobility and enhance quality of life. Our group recognize the significance of biomechanics in musculoskeletal disease management, specifically in the domain of KOA gait re-training. Gait re-training, a therapeutic intervention aimed at modifying abnormal walking patterns, has shown promising results in managing KOA. However, accurately assessing and quantifying biomechanical metrics during gait re-training has remained a challenge, hindering the optimization of treatment strategies.